A lot of people start HRT using blockers such as Spironolactone to suppress Testosterone with the goal of achieving typical cis women levels for optimum feminization. Some people even try a “low and slow” method of antiandrogen monotherapy for several months before starting Estradiol therapy. One frequent question is whether Estradiol Monotherapy (only dosing Estradiol […]
Category: Spironolactone
What are the best Antiandrogens? Limited studies exist.
When I asked my Doctor about whether Spironolactone actually worked, he said it worked well for some people. I mentioned the lack of consensus in studies about efficacy and he simply stated that antiandrogen studies were very limited and pointed to this reference: https://onlinelibrary.wiley.com/doi/pdf/10.1111/cen.14329 5 | CONCLUSIONAntiandrogens are frequently added to estradiol to assist withfeminization and suppression […]
Maximum Transfeminine breast development. What is the hard evidence?
A question that comes up often is whether high Estradiol, early Progesterone, or early/high Spironolactone may stunt or limit good breast development. There are limited studies on this topic; however, here are some resources to help shed some light: 1. High Estradiol Gender Analysis has a citation for high Estradiol and resultant poor breast development. […]