A lot of people start HRT using blockers such as Spironolactone to suppress Testosterone with the goal of achieving typical cis women levels for optimum feminization. Some people even try a “low and slow” method of antiandrogen monotherapy for several months before starting Estradiol therapy. One frequent question is whether Estradiol Monotherapy (only dosing Estradiol […]
Category: Bicalutamide
Bicalutamide has no established safety guidelines.
When I asked my first HRT (Hormone Replacement Therapy) doctor about trying Bicalutamide 50mg they simply said no. That first doctor was Plume in case you are trying to use Plume to get your hands on Bicalutamide – they will flatly decline for safety concerns. The thing about Bicalutamide is that there are not a […]
My experience with Bicalutamide was not great…
Anecdotal First Hand Experience I had such high hopes for Bicalutamide that I switched doctors primarily to give it a try, because my prior doctor was unwilling. There are no clinical guidelines for safety, so I came up with my own: 1x 50mg Wait 48 hours for any adverse reaction 1x 50mg Wait 48 hours […]
What are the best Antiandrogens? Limited studies exist.
When I asked my Doctor about whether Spironolactone actually worked, he said it worked well for some people. I mentioned the lack of consensus in studies about efficacy and he simply stated that antiandrogen studies were very limited and pointed to this reference: https://onlinelibrary.wiley.com/doi/pdf/10.1111/cen.14329 5 | CONCLUSIONAntiandrogens are frequently added to estradiol to assist withfeminization and suppression […]