A lot of people start HRT using blockers such as Spironolactone to suppress Testosterone with the goal of achieving typical cis women levels for optimum feminization. Some people even try a “low and slow” method of antiandrogen monotherapy for several months before starting Estradiol therapy. One frequent question is whether Estradiol Monotherapy (only dosing Estradiol … Continue reading Can Estradiol Monotherapy work for you? Will you need antiandrogens?